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beta-2 Microglobulin anticorps

Cet anticorps Souris Monoclonal détecte spécifiquement beta-2 Microglobulin dans WB, FACS et IHC (fro). Il présente une réactivité envers Rat.
N° du produit ABIN119386

Aperçu rapide pour beta-2 Microglobulin anticorps (ABIN119386)

Antigène

Voir toutes beta-2 Microglobulin (B2M) Anticorps
beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Reactivité

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Rat

Hôte

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Souris

Clonalité

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Monoclonal

Conjugué

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Cet anticorp beta-2 Microglobulin est non-conjugé

Application

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone

TLD-3H12B
  • Specificité

    This antibody recognises beta-2 microglobulin, expressed at the surface of most cells in association with MHC Class I molecules.

    Purification

    Affinity chromatography on Protein G

    Immunogène

    Rat microglial cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse MOM myeloma cell line.

    Isotype

    IgG1
  • Indications d'application

    Flow cytometry: 1/10 - 1/20, use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunohistochemistry on frozen sections. Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    PBS, pH 7.4 containing 0.09 % Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène

    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

    Autre désignation

    beta-2-Microglobulin

    Sujet

    Beta 2 Microglobulin non-covalently associates with the 44 kDa alpha chain to form the HLA Class I antigen complex. Human beta 2 Microglobulin associated with HLA Class I antigens are expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.Synonyms: B2M, Beta 2 microglobulin, Beta-2 microglobulin

    ID gène

    24223

    NCBI Accession

    NP_036644

    UniProt

    P07151

    Pathways

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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